Kalonji’s therapeutic use was initiated after the advent of Islam, since, Prophet Muhammad (Pbuh) mentioned its therapeutic efficacy and potential of cure. Hazrat Abu Hurairah states - “I have heard from Rasool Allah (Pbuh) that there is cure for every disease in black seeds except death and black seeds are shooneez.” Salim Bin Abdullah narrates with reference to his father Hazrat Abdullah Bin Omar that Rasool Allah (Pbuh) said, “Let fall these black seeds upon you, these contain cure for all diseases except death.” The same narration is found in Sanad-e-Ahmed from Hazrat Aisha (t) and in Ibn-al-Jozi and Trimizi from Abu Huraira. Hazrat Buraidah narrates that Prophet Muhammad (Pbuh) stated - “Shooneez is cure for all ailments except death.” It is stated in the books of seerat that Nabi-e-Akram (Pbuh) himself used to take these seeds for therapeutic purpose but with the syrup of Honey.
Seeds are considered stimulant, carminative, antiinflammatory, diuretic, diaphoretic, antibilious, emmenagogue and galactagogue. Used in allergies, colds and fevers. It is also useful in a wide variety of other diseases and conditions including bilious ailments, cancer, colic, corns, eruptions, headaches, jaundice, orchitis, puerperal fever, sclerosis, stomachache, swellings, tumors of the abdomen and eyes, and warts.
For upper respiratory conditions, at least a few of its constituents have shown an antihistamine-like action, which explains is positive effects for upper respiratory diseases including asthma, bronchitis, cough and flu. The seeds promote menstrual periods.
It also has a positive effect on liver diseases. One of its most obvious uses is for diarrhoea and dysentery, combined with astringents. The seeds also are a rich source of sterols, especially beta-sitosterol, which is known to have anticarcinogenic activity. This substantiates its use for indurations and/or tumors of the abdomen, eyes and liver.
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