HCA can inhibit an enzyme in cells, citrate lyase, which is needed for the conversion of carbohydrates into fat. In the cell, carbohydrates are broken down into citrate compounds, which are then converted (by citrate lyase) into another compound; acetyl coenzyme A (acetyl CoA) – the metabolic building block for fat synthesis. By blocking the conversion of citrate into acetyl-CoA, HCA can suppress fat synthesis.
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