Erythropoietin

Additional Details

Erythropoietin is available as a therapeutic agent produced by recombinant DNA technology in mammalian cell culture. It is used in treating anaemia resulting from chronic kidney disease and myelodysplasia, from the treatment of cancer (chemotherapy and radiation), and from other critical illnesses (heart failure).

 Available forms as biomedicine

• Epogen which is made by Amgen
• Eporise mady by Zuventus.
• Epotin which is made by Gulf Pharmaceutical Ind. (JULPHAR)
• Betapoietin which is made by CinnaGen and Zahravi
• ReliPoietin which is made by Reliance Life Sciences Pvt. Ltd
• Epokine which is made by Intas Biopharmaceutica Pvt. Ltd
• Shanpoietin which is made by Shantha Biotechnincs Ltd
• Anemia due to chronic kidney disease

In patients that require dialysis (have stage 5 chronic kidney disease(CKD)), iron should be given with erythropoietin.[12] Dialysis patients in the US are most often given Epogen; outside of the US other brands of epoetin may be used.

Outside of people on dialysis, erythropoietin is used most commonly to treat anemia in people with chronic kidney disease that are not on dialysis (those in stage 3 or 4 CKD and those living with a kidney transplant). There are two types of erythropoietin (and three brands) for people with anemia due to chronic kidney disease (not on dialysis):

• Epoetin (Procrit (also known as Eprex), NeoRecormon)
• Darbepoetin (Aranesp).
• Methoxy Polyethylene Glycol-Epoetin Beta (MIRCERA)
• Brands available in the USA include: Epoetin (Procrit and Epogen).
• Anemia due to treatment for cancer
• This section requires expansion.