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P E surgical gloves are made from synthetic polyisoprene which provide similar properties to latex (natural rubber). In fact, polyisoprene has a molecular structure that is very similar to natural rubber. Polyisoprene is regarded as a "latex" glove without the harmful protein found in latex which is responsible for latex allergies. Like other surgical glove materials, polyisoprene surgical gloves are available with polymer inner coating so donning gloves are easier even when hands are damp or dry. Of all material used to make surgical gloves, polyisoprene is the most expensive material. Even so, most surgical glove manufacturers offer polyisoprene gloves options as adoption continue to increase due to similar properties as latex.